| Date | Location | Result | |
| 11-14-09 | Defiance, OH | Defiance 35, Bluffton 0 | Box score |
| 11-07-09 | Cincinnati, OH | Mount St. Joseph 24, Defiance 16 | Box score |
| 10-31-09 | Defiance, OH | Hanover 30, Defiance 27 | Box score |
| 10-24-09 | Anderson, IN | Defiance 20, Anderson 7 | Box score |
| 10-17-09 | Terre Haute, IN | Defiance 28, Rose-Hulman 21 | Box score |
| 10-10-09 | Defiance, OH | Manchester 20, Defiance 19 | Box score |
| 10-03-09 | Franklin, IN | Franklin 41, Defiance 14 | Box score |
| 09-19-09 | Angola, IN | Trine 40, Defiance 9 | Box score |
| 09-12-09 | Defiance, OH | Adrian 31, Defiance 16 | Box score |
| 09-05-09 | Defiance, OH | Defiance 13, Muskingum 7 | Box score |